The pace of change is a characteristic of the 21st century, and sometimes the pace of these changes is increasing, and most societies ignore their perceptions. The prevailing atmosphere of today's economy is the risk associated with uncertainty and can not be countered by these corrective actions and these changes as well as the creation of a sustainable competitive advantage. The first generation of universities, the mission of education and the second generation, in addition to its previous task, is also responsible for research, but the third-generation academic, called the Entrepreneur's University, is also a leading actor in the country's economic growth and development, in addition to its teaching and research function. Looking at the world's top universities in internationally acclaimed systems, one can get, between academic rank and political, economic, and political power. . . Communities have a meaningful relationship. An entrepreneurial university is not a university or organization, but a structure or culture. A culture that brings creative and innovative growth and development to the surrounding environment. Accordingly, in this paper, after the concept of the term Babayan entrepreneurship, the problems of today's universities with the industrial approach and transformation in the mission of universities, the need for entrepreneurship in the context of university and the role of the university in industrial development, then the role of culture as an academic tool in establishing the concept of university The entrepreneur was referred to as well as the morale and culture in the academic environment.